LIVING CURES

LIVING CURES

LIVING CURES

[Re]engineering evolution into Living Cures platform for novel immunotherapies

[Re]engineering evolution into Living Cures platform for novel immunotherapies

[Re]engineering evolution into Living Cures platform for novel immunotherapies

FOUNDATIONAL TECHNOLOGY

Prokarium's Foundational technology leverages inherent anti-tumor mechanisms of a proprietary strain of bacteria (ZH9) as a microbial immunotherapy platform

• Naturally tumor targeting and oncolytic
• Overcomes the suppressive tumor microenvironment
• Targets multiple pathways to elicit strong anti-tumor immunity
• Extensive opportunities to deliver diverse cargo

Proprietary ZH9 Chassis Strain

FOUNDATIONAL TECHNOLOGY

Prokarium's Foundational technology leverages inherent anti-tumor mechanisms of a proprietary strain of bacteria (ZH9) as a microbial immunotherapy platform

• Naturally tumor targeting and oncolytic
• Overcomes the suppressive tumor microenvironment
• Targets multiple pathways to elicit strong anti-tumor immunity
• Extensive opportunities to deliver diverse cargo

Proprietary ZH9 Chassis Strain

MARKET
MARKET
APPLICATIONS
APPLICATIONS
ABOUT US

TEAM

BOARD OF DIRECTORS

ADVISORS

Ibs Mahmood
CEO
Livija Deban, PhD
CSO
Dara Henry, PhD
COO
Josi Holz, MD, PhD
CMO
Julia Jones, FCA
CFO
Nick Glanville, PhD
VP of Research

TEAM

BOARD OF DIRECTORS

ADVISORS

Ibs Mahmood
CEO
Livija Deban, PhD
CSO
Dara Henry, PhD
COO
Josi Holz, MD, PhD
CMO
Julia Jones, FCA
CFO
Nick Glanville, PhD
VP of Research
PIPELINE
Indication
Discovery
Discovery
Preclinical
Preclinical
IND-Enabling
IND-Enabling
Phase I

ZH9 - Bladder cancer Non-muscle invasive

Phase I initiated in US

Indication

ZH9 - Bladder cancer Non-muscle invasive

Phase I initiated in US

ZH9 - Bladder cancer Muscle invasive

Combination with checkpoint inhibitors

Indication

ZH9 - Bladder cancer Muscle invasive

Combination with checkpoint inhibitors

IO Prime

First-in-class oral immune fitness agent ready to enter the clinic

Indication

IO Prime

First-in-class oral immune fitness agent ready to enter the clinic

Living Cures Platform

Discovery cargo-delivery IO platform

Indication

Living Cures Platform

Discovery cargo-delivery IO platform

CAREERS

Contact

Contact

Contact

London Bioscience Innovation Centre,
2 Royal College St,
NWI ONH, London, UK

London Bioscience Innovation Centre,
2 Royal College St,
NWI ONH, London, UK

prokarium

prokarium

Design the future with us

Design the future with us

Design the future with us

Prokarium 2026 © All Rights Reserved

Prokarium 2026 © All Rights Reserved

Prokarium 2026 © All Rights Reserved